![]() There are no initial or early symptoms in most cases, but late symptoms may include fatigue due to anemia, bone pain, paralysis from spinal metastases, and renal failure from bilateral ureteral obstruction.ĭiagnosis is primarily based on prostate-specific antigen (PSA) testing and transrectal ultrasound-guided (TRUS) prostate tissue biopsies, although PSA testing for screening remains controversial. įortunately, most prostate cancers tend to grow slowly and are low-grade with relatively low risk and limited aggressiveness. Globally, prostate cancer is the most commonly diagnosed malignancy in more than fifty percent of countries (112 of 185). This amounted to 1,414,249 newly diagnosed cases and 375,000 deaths worldwide yearly from this disease in 2020. ![]() ![]() Worldwide, prostate cancer is the most commonly diagnosed male malignancy and the fifth leading cause of cancer death in men. ![]()
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